Marine Natural Products Lab

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Malcolm Mcculloch

 Research Interests

Drug discovery
Organic synthesis
Natural products
 
Education
PhD, Australian National University (2003-2006)
Bachelor of Science (1st Hons), Australian National University (1998-2002)
Bachelor of Commerce, Australian National University (1998-2002)
           
Work Experience
 
2009-
 
2007-2009
Laboratory of Prof. Chris M. Ireland, University of Utah.
Post Doctoral Fellow
 
2002-2006
Department of Chemistry, Australian National University
Laboratory Demonstrator (organic, inorganic, general)
 
2004-2006
Department of Chemistry, Australian National University
Tutor (organic, general)
 
Publications
 
  1. McCulloch, Malcolm W. B.; Coombs, Gary S.; Banerjee, Nikhil; Bugni, Tim S.; Cannon, Kendell M.; Harper, Mary Kay; Veltri, Charles A.; Virshup, David M.; Ireland, Chris M. ‘Psammaplin A as a general activator of cell based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives’, Bioorganic and Medicinal Chemistry. 2009, 17, 2189-2198.
  2. Barrow, Russell A.; McCulloch, Malcolm W. B.  ‘Linear naphtho-g-pyrones : A naturally occurring scaffold of biological importance’, Mini-Reviews in Medicinal Chemistry20099, 273-292.
  3. Bugni, Tim S.; Harper, Mary Kay; McCulloch, Malcolm W. B.; Reppart, Jason; Ireland, Chris M. ‘Fractionated marine invertebrate extract libraries for drug discovery’, Molecules 2008, 13(6), 1372-1383.
  4. McCulloch, Malcolm W. B.; Barrow, Russell A. ‘A metalation strategy for the construction of functionalized naphthalenes: the first synthesis of guieranone A’, Tetrahedron Letters2005, 46(44), 7619-7621.
  5. McCulloch, Malcolm W. B.; Barrow, Russell A. ‘Towards a synthesis of naphthalene derived natural products’, Molecules2005, 10(10), 1272-1278.